Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trpc7tm1.1Lbi
Name:	transient receptor potential cation channel, subfamily C, member 7; targeted mutation 1.1, Lutz Birnbaumer
MGI ID:	MGI:5296004
Synonyms:	Trpc7tm1.1Kofu
Gene:	Trpc7  Location: Chr13:56920911-57043778 bp, - strand  Genetic Position: Chr13, 30.27 cM, cytoband B2
Alliance:	Trpc7tm1.1Lbi page

Germline Transmission:	Earliest citation of germline transmission: J:176849
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 5. Cre-mediated recombination removed the neo cassette and exon 5. The absence of transcripts with exon 5 was confirmed by RT-PCR. (J:176849)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trpc7 Mutation:	38 strains or lines available

Original:	J:176849 Perez-Leighton CE, et al., Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits. Eur J Neurosci. 2011 Mar;33(5):856-67
All:	10 reference(s)