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Gene Expression Data
Assay Details
Assay
Reference: J:42455 Dunwoodie SL, et al., Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo. Development. 1997 Aug;124(16):3065-76
Assay type: RNA in situ
MGI Accession ID: MGI:5295436
Gene symbol: Dll3
Gene name: delta like canonical Notch ligand 3
Probe: Dll3 cDNA2
Probe preparation: Antisense RNA
Visualized with: Alkaline phosphatase
Assay notes: It is possible that Probe Dll3 cDNA3 (MGI:2446514) was used for this assay.
Results
Specimen 7A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube lateral wall Present Regionally restricted 7A Expression in the basal surface of the ventricular zone, along its dorsoventral extent. A broader band of expression at the basal plate.
TS15: dorsal root ganglion Present 7A
TS15: neural tube floor plate Absent 7A
TS15: neural tube roof plate Absent 7A

Specimen 7B: embryonic day 11.5 (more )
Note: Double labeled: red - Dll3; green - BrdU.
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Regionally restricted 7D , 7C , 7B Expression in postmitotic cells lateral to the cells labeled with BrdU along most of the dorsoventral extent. At the region opposite the basal plate, cells expressing Dll3 and cells labelled with BrdU are scattered between the basal and lumenal surface.

Specimen 7E: embryonic day 11.0 (more )
Note: Double labeled: red - Dll3; green - Isl1 (assay MGI:5295451) and Isl2 (assay MGI:5295452).
Structure Level Pattern Image Note
TS19: neural tube ventricular layer Present Regionally restricted 7E , 7F Most of the cells that express Dll3 are devoid of the islet-1/2 protein. Coexpression is seen in occasional cells adjacent to the basal plate.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord lateral wall Present Reduced expression.

Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord lateral wall Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory