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Bcl2l12tm1e(EUCOMM)Hmgu
Targeted Allele Detail
Summary
Symbol: Bcl2l12tm1e(EUCOMM)Hmgu
Name: BCL2 like 12; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:5294994
Gene: Bcl2l12  Location: Chr7:44640646-44647011 bp, - strand  Genetic Position: Chr7, 29.07 cM, cytoband B2
IMPC: Bcl2l12 gene page
Mutation
origin
Mutant Cell Lines:  HEPD0764_1_A06, HEPD0764_1_A07, HEPD0764_1_A08, HEPD0764_1_B07, HEPD0764_1_B08, HEPD0764_1_C06, HEPD0764_1_C08, HEPD0764_1_D05, HEPD0764_1_D06, HEPD0764_1_E05, HEPD0764_1_E06, HEPD0764_1_E07, HEPD0764_1_G05, HEPD0764_1_G06, HEPD0764_1_G07, HEPD0764_1_G08, HEPD0764_1_H05, HEPD0764_1_H07
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 44644757 of Chromosome 7 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Bcl2l12 Mutation:  27 strains or lines available
References
Original:  J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory