Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pbktm1Zgdo
Name:	PDZ binding kinase; targeted mutation 1, Zigang Dong
MGI ID:	MGI:5293435
Gene:	Pbk  Location: Chr14:66043337-66055271 bp, + strand  Genetic Position: Chr14, 34.36 cM
Alliance:	Pbktm1Zgdo page

Germline Transmission:	Earliest citation of germline transmission: J:176985
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Not Specified     No details provided. (J:176985)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pbk Mutation:	37 strains or lines available

Original:	J:176985 Li S, et al., T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway. J Biol Chem. 2011 Aug 26;286(34):29601-9
All:	3 reference(s)