Gene Expression Data
Assay Details
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Assay
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Reference:
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J:73069
Wang W, et al., Hmx2 homeobox gene control of murine vestibular morphogenesis. Development. 2001 Dec;128(24):5017-29
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5286121
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Gene symbol:
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Hmx2
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Gene name:
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H6 homeobox 2
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2A:
embryonic day 8.5; Hmx2tm1Tlu/Hmx2 +
(more  )
Specimen
2A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2B:
embryonic day 9.5; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
2B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: otocyst |
Strong |
Regionally restricted |
2B
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Expression is present in the anterior portion of the otic vesicle.
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| TS15: branchial arch |
Present |
Regionally restricted |
2B
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Expression is present in the cleft between the first and second branchial arches.
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Specimen
2C:
embryonic day 10.5; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
2C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: otocyst |
Present |
Regionally restricted |
2C
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Expression is present in the anterio-dorsal portion.
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| TS17: branchial arch |
Present |
Regionally restricted |
2C
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Expression is present in the cleft between the first and second branchial arches.
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Specimen
2D:
embryonic day 12.0; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
2D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3A:
embryonic day 13.5; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
3A:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3C:
embryonic day 18.5; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
3C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
Not shown:
embryonic day 18.5; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
Not shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: inner ear |
Present |
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3D
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There are multiple inner ear defects in the homozygote.
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Specimen
3E:
embryonic day 18.5; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
3E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: inner ear |
Present |
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3F
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There are multiple inner ear defects in the homozygote.
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Specimen
6A:
embryonic day 11.5; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
6A:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: inner ear vestibular component |
Present |
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6A
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Expression is present in the entire dorsal otic vesicle excluding the otic epithelium cells destined to form the endolymphatic duct and sac.
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| TS19: endolymphatic appendage |
Absent |
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6A
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Expression is present in the entire dorsal otic vesicle excluding the otic epithelium cells destined to form the endolymphatic duct and sac.
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Specimen
6B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: inner ear |
Present |
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6B
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There are morphological alternations in the homozygote.
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Specimen
6C:
embryonic day 12.0; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
6C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
6D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: inner ear |
Present |
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6D
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There are morphological alternations in the homozygote.
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Specimen
6E:
embryonic day 12.0; Hmx2tm1Tlu/Hmx2 +
(more )
Specimen
6E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
6F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Hmx2tm1Tlu/Hmx2tm1Tlu
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: inner ear |
Present |
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6F
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There are morphological alternations in the homozygote.
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