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Gene Expression Data
Assay Details
Assay
Reference: J:40722 Shirasawa S, et al., Enx (Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon. Nat Med. 1997 Jun;3(6):646-50
Assay type: RNA in situ
MGI Accession ID: MGI:5286105
Gene symbol: Tlx2
Gene name: T cell leukemia, homeobox 2
Probe: Enx cDNA
Probe preparation: Antisense labelled with P33 RNA
Results
Specimen 1b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sympathetic nervous system Present Regionally restricted 1b Expression is in the sympathetic chain, superior cervical ganlia, celiac ganglia and sympathoadrenal cells.
TS20: parasympathetic nervous system Present Regionally restricted 1b Expression is in ganglia of the heart and salivary gland.
Specimen 1c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: gut Present 1c
Specimen 1d: postnatal day 18 (more )
Structure Level Pattern Image Note
TS28: small intestine Present Regionally restricted 1d Absent in proximal small intestine.
Specimen 1e: postnatal day 18 (more )
Structure Level Pattern Image Note
TS28: ileum Strong Regionally restricted 1e Expression is in myenteric and submucosal ganglia in the distal ileum.
Specimen 1f: postnatal day 18 (more )
Structure Level Pattern Image Note
TS28: colon Strong Regionally restricted 1f Expression is in myenteric and submucosal ganglia in the proximal colon.
Specimen 1g: postnatal day 18 (more )
Structure Level Pattern Image Note
TS28: colon Strong Regionally restricted 1g Expression is in myenteric and submucosal ganglia in the distal colon and rectum.
TS28: rectum Strong Regionally restricted 1g Expression is in myenteric and submucosal ganglia in the distal colon and rectum.
Specimen Not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: gut Present
Specimen Not shown Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: parasympathetic ganglion Present Regionally restricted Expression is in parasympathetic neurons of the heart.
TS28: adrenal medulla Present Single cells Expression is in chromaffin cells.
Specimen Not shown P24: postnatal day 24 (more )
Structure Level Pattern Image Note
TS28: ileum Present Regionally restricted Expression is in myenteric and submucosal ganglia in the distal ileum.
TS28: colon Present Regionally restricted Expression is in myenteric and submucosal ganglia in the colon.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory