Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcnn2bc-8J
Name:	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; bouncy 8 Jackson
MGI ID:	MGI:5140705
Gene:	Kcnn2  Location: Chr18:45401927-45818950 bp, + strand  Genetic Position: Chr18, 24.34 cM, cytoband C
Alliance:	Kcnn2bc-8J page

Strain of Origin:

C57BL/6J

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: A G-to-A point mutation at coding nucleotide 1159/1954/1984 of the cDNA (NM_080465/ENSMUST00000066890/NM_001312905) results in a valine to isoleucine substitution at position 387/652/662 of the encoded protein (NP_536713:p.V387I, ENSMUSP00000067884:p.V652I, NP_001299834:p.V662I). (J:222308) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kcnn2 Mutation:	43 strains or lines available

Original:	J:174667 Karst SY, et al., A remutation to bouncy on the C57BL/6J background, bouncy 8 Jackson. MGI Direct Data Submission. 2011;
All:	2 reference(s)