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Gene Expression Data
Assay Details
Assay
Reference: J:81589 Wada H, et al., In situ expression of heat shock proteins, Hsc73, Hsj2 and Hsp86 in the developing tooth germ of mouse lower first molar. Histochem J. 2002 Mar-Apr;34(3-4):105-9
Assay type: RNA in situ
MGI Accession ID: MGI:5056456
Gene symbol: Hsp90aa1
Gene name: heat shock protein 90, alpha (cytosolic), class A member 1
Probe: Hsp86 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1C: embryonic day 11.0 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component mesenchyme Present Regionally restricted 1C Expression is diffuse in the mesenchymal cells corresponding to the area where the first molar would be formed.
TS18: oral epithelium Weak Regionally restricted 1C Expression is in oral mucosal cells.
Specimen 1F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mandibular process mesenchyme Present Regionally restricted 1F Expressing cells are at the area where the tooth germ will be formed, stronger on the buccal side than the lingual side.
Specimen 1I: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: lower jaw molar mesenchyme Present 1I
TS21: tooth bud Present 1I
Specimen 1L: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar mesenchyme Weak 1L
TS22: lower jaw molar enamel organ Present Regionally restricted 1L Expression is in odontogenic epithelial cells.
TS22: oral epithelium Present Regionally restricted 1L Expression is in oral mucosal cells.
Specimen 2C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: lower jaw molar enamel organ Strong Regionally restricted 2C Expression is in the lateral odontogenic epithelial cells and is weak in the central area of the enamel organ, the primary enamel knot.
TS23: primary enamel knot Strong Regionally restricted 2C Expression is in the lateral odontogenic epithelial cells and is weak in the central area of the enamel organ, the primary enamel knot.
TS23: dental sac Weak 2C
TS23: lower jaw molar dental papilla Weak 2C
TS23: cap stage tooth Present Regionally restricted 2C
Specimen 2F: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar dental papilla Strong 2F
TS24: lower jaw molar enamel organ Strong 2F
Specimen 2I: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: inner enamel epithelium Present 2I
TS25: lower jaw molar dental papilla Present Regionally restricted 2I Expression is in cells facing the inner epithelial layer.
TS25: bell stage tooth Present Regionally restricted 2I
Specimen 2L: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: inner enamel epithelium Present 2L
TS26: lower jaw molar dental papilla Present Regionally restricted 2L Expression is in cells facing the inner epithelial layer (odontoblasts).
TS26: bell stage tooth Present Regionally restricted 2L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory