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Yeae Gene Detail
Summary
  • Symbol
    Yeae
  • Name
    experimental allergic encephalomyelitis susceptibility region of Chr Y
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:5007670
  • Alliance
    gene page
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome Y, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Variations in expression of alleles on specific backgrounds result in variable susceptibility to experimental allergic encephalomyelitis. In utero exposure of XX fetuses to XY fetuses of appropriate genotype results in a disease course in females that resembles that of their male littermates.
References
more
  • Summaries
    All 2
    Phenotypes 2
  • Earliest
    J:110221 Teuscher C, et al., Evidence that the Y chromosome influences autoimmune disease in male and female mice. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8024-9
  • Latest
    J:144809 Spach KM, et al., Cutting edge: the Y chromosome controls the age-dependent experimental allergic encephalomyelitis sexual dimorphism in SJL/J mice. J Immunol. 2009 Feb 15;182(4):1789-93
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory