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Acsl5tm1Lex
Targeted Allele Detail
Summary
Symbol: Acsl5tm1Lex
Name: acyl-CoA synthetase long-chain family member 5; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007008
Gene: Acsl5  Location: Chr19:55240298-55285060 bp, + strand  Genetic Position: Chr19, 51.3 cM, cytoband D2
Alliance: Acsl5tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA portion of the coding region was targeted by homologous recombination. Coding exons 14 through 16 were targeted (NCBI accession BC031544.1). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Acsl5 Mutation:  53 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory