Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cacna1atm1.2Sher
Name:	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; targeted mutation 1.2, Stefan Herlitze
MGI ID:	MGI:4949729
Synonyms:	Cacna1anull-
Gene:	Cacna1a  Location: Chr8:85065268-85366875 bp, + strand  Genetic Position: Chr8, 40.95 cM
Alliance:	Cacna1atm1.2Sher page

Germline Transmission:	Earliest citation of germline transmission: J:170451
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediation removed the citrine reporter and duplicate exon 1 while the floxed neo cassette remains intact. (J:170451)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacna1a Mutation:	115 strains or lines available

Original:	J:170451 Mark MD, et al., Delayed Postnatal Loss of P/Q-Type Calcium Channels Recapitulates the Absence Epilepsy, Dyskinesia, and Ataxia Phenotypes of Genomic Cacna1A Mutations. J Neurosci. 2011 Mar 16;31(11):4311-26
All:	1 reference(s)