Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Zic2m1Nisw
Name:	zinc finger protein of the cerebellum 2; mutation 1, Lee Niswander
MGI ID:	MGI:4943187
Synonyms:	Line7-12
Gene:	Zic2  Location: Chr14:122712847-122717264 bp, + strand  Genetic Position: Chr14, 65.97 cM
Alliance:	Zic2m1Nisw page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) (Hypomorph) Mutation:    Nucleotide substitutions   Mutation details: ENU mutagenesis induced A to T transversion at position 986 (A986T) that changes glutamic acid to valine in the zinc finger domain. The protein level is not affected in this hypomorphic allele. (J:169832, J:214510)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zic2 Mutation:	41 strains or lines available

Original:	J:169832 Niswander L, Direct Data Submission 2011/03/29. MGI Direct Data Submission. 2011;
All:	3 reference(s)