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Gene Expression Data
Assay Details
Assay
Reference: J:169194 Walsh T, et al., Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82. Am J Hum Genet. 2010 Jul 9;87(1):90-4
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4942380
Gene symbol: Gpsm2
Gene name: G-protein signalling modulator 2 (AGS3-like, C. elegans)
Antibody: anti-Gpsm2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2C: embryonic day 16.5 (more )
Note: Double labeled: green - Gpsm2; red - Myo6 (assay MGI:4942390).
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 2C Expression is at the apical surfaces of the hair and supporting cells in the cochlea.
Specimen 2D: embryonic day 16.5 (more )
Note: Double labeled: green - Gpsm2; red - Myo6 (assay MGI:4942390).
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 2D Expression is at the apical surfaces of the hair and supporting cells in the cochlea.
Specimen 2E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 2E Expression extends throughout the greater epithelial ridge.
Specimen 2F: embryonic day 16.5 (more )
Note: Double labeled: green - Gpsm2; red - Myo6 (assay MGI:4942390).
Structure Level Pattern Image Note
TS24: utricle Present Scattered 2F Expression is at the apical surfaces of the hair and supporting cells.
Specimen 2G: postnatal day 0 (more )
Note: Double labeled: green - Gpsm2; red - Myo6 (assay MGI:4942390).
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 2G Expression is at the apical surfaces of the hair and supporting cells in the cochlea.
Specimen 2H: postnatal day 0 (more )
Note: Double labeled: green - Gpsm2; red - Myo6 (assay MGI:4942390).
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 2H Expression is at the apical surfaces of the hair and supporting cells in the cochlea.
Specimen 2I: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 2I Expression extends throughout the greater epithelial ridge.
Specimen 2J: postnatal day 0 (more )
Note: Double labeled: green - Gpsm2; red - Myo6 (assay MGI:4942390).
Structure Level Pattern Image Note
TS27: utricle Present Regionally restricted 2J Expression is at the apical surfaces of the hair and supporting cells.
Specimen Not shown E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: saccule Present Regionally restricted Expression is at the apical surfaces of the hair and supporting cells.
Specimen Not shown P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: crista ampullaris Present Regionally restricted Expression is at the apical surfaces of the hair and supporting cells.
TS27: saccule Present Regionally restricted Expression is at the apical surfaces of the hair and supporting cells.
Specimen S2A: postnatal day 0 (more )
Note: Double labeled: green - Gpsm2; red - Myo6 (assay MGI:4942390).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted S2A Expression is in pillar cells.
Specimen S2B: postnatal day 15 (more )
Note: Double labeled: green - Gpsm2; red - Pvalb (assay MGI:4942391).
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2B Expression is in the inner and outer pillar cells.
Specimen S2C: postnatal day 60 (more )
Note: Double labeled: green - Gpsm2; red - Pvalb (assay MGI:4942391).
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2C Expression is in the inner and outer pillar cells, specifically in the head region of the inner pillar cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory