Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Defa2-Myd88)1Lvh
Name:	transgene insertion 1, Lora Hooper
MGI ID:	MGI:4941629
Synonyms:	Cr2-FlagMyd88
Transgene:	Tg(Defa2-Myd88)1Lvh  Location: unknown
Alliance:	Tg(Defa2-Myd88)1Lvh page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Defa2-Myd88)1Lvh expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Myd88 (MGI:108005)   Mutation details: FLAG-tagged Myd88 was placed under the transcriptional control of nucleotides -6500 to +134 of the mouse Defa2 (defensin, alpha, 2; also known as cryptdin 2) gene. Human growth hormone (hGH, +3 to +2150) was placed immediately downstream to enhance transgenic expression, but is not transcribed. (J:169662)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:169662 Vaishnava S, et al., Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20858-63
All:	1 reference(s)