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Tg(Myh6/tetO-Itpr2)4.9Jmol
Transgene Detail
Summary
Symbol: Tg(Myh6/tetO-Itpr2)4.9Jmol
Name: transgene insertion 4.9, Jeffery D Molkentin
MGI ID: MGI:4940824
Synonyms: IP3R2 - low transgenic
Transgene: Tg(Myh6/tetO-Itpr2)4.9Jmol  Location: unknown  
Alliance: Tg(Myh6/tetO-Itpr2)4.9Jmol page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(Myh6/tetO-Itpr2)4.9Jmol expresses 1 gene
 
Mutation detailscDNA encoding mouse Iptr2 was cloned into the mouse inducible Myh6 (myosin, heavy polypeptide 6, cardiac muscle, alpha) tetO promoter. Lines 3.11 (high expressor) and 4.9 (low expressor) were generated. (J:169368)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:169368 Nakayama H, et al., The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. Circ Res. 2010 Sep 3;107(5):659-66
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory