Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Syt12tm1.1Sud
Name:	synaptotagmin XII; targeted mutation 1.1, Thomas C Sudhof
MGI ID:	MGI:4940391
Synonyms:	Syt12 S97A KI
Gene:	Syt12  Location: Chr19:4495936-4527171 bp, - strand  Genetic Position: Chr19, 4.07 cM, cytoband A
Alliance:	Syt12tm1.1Sud page

Germline Transmission:	Earliest citation of germline transmission: J:178819
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted Mutations:    Insertion, Nucleotide substitutions   Mutation details: Serine 97 (exon 4) was mutated to alanine (S97A) and exons 4-6 were flanked by loxP sites in the targeting vector. An FRT-flanked neomycin cassette was also incorporated. Flp-mediated recombination removed the neo cassette. (J:178819)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Syt12 Mutation:	16 strains or lines available

Original:	J:178819 Sudhof TC, Direct Data Submission 2011/03/10. MGI Direct Data Submission. 2012;
All:	2 reference(s)