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Tnfrsf14tm1Csj
Targeted Allele Detail
Summary
Symbol: Tnfrsf14tm1Csj
Name: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); targeted mutation 1, Choon-Soo Jeong
MGI ID: MGI:4940320
Gene: Tnfrsf14  Location: Chr4:155006390-155013020 bp, - strand  Genetic Position: Chr4, 85.81 cM
Alliance: Tnfrsf14tm1Csj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169369
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 4.8 kb fragment extending from intron 4 through intron 9 was replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on bone marrow cells. (J:169369)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfrsf14 Mutation:  20 strains or lines available
References
Original:  J:169369 Kim WK, et al., Role of TNFR-related 2 mediated immune responses in dextran sulfate sodium-induced inflammatory bowel disease. Mol Cells. 2011 Feb;31(2):99-104
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory