About   Help   FAQ
Pnpla3tm1Eek
Targeted Allele Detail
Summary
Symbol: Pnpla3tm1Eek
Name: patatin-like phospholipase domain containing 3; targeted mutation 1, Erin E Kershaw
MGI ID: MGI:4939497
Gene: Pnpla3  Location: Chr15:84052038-84071437 bp, + strand  Genetic Position: Chr15, 39.78 cM, cytoband E3
Alliance: Pnpla3tm1Eek page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168857
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neo cassette. The absence of transcript expression was confirmed by RNA analysis on white adipose tissue, brown adipose tissue, adrenal, and liver extracts. (J:168857)
Generation of the Pnpla3tm1Eek allele
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pnpla3 Mutation:  28 strains or lines available
References
Original:  J:168857 Basantani MK, et al., Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome. J Lipid Res. 2011 Feb;52(2):318-29
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory