Aldh5a1tm1(EUCOMM)Wtsi
Targeted Allele Detail
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Symbol: |
Aldh5a1tm1(EUCOMM)Wtsi |
Name: |
aldhehyde dehydrogenase family 5, subfamily A1; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4881069 |
Gene: |
Aldh5a1 Location: Chr13:25091562-25121644 bp, - strand Genetic Position: Chr13, 10.77 cM
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IMPC: |
Aldh5a1 gene page |
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Mutant Cell Lines: |
EPD0711_2_A01, EPD0711_2_A03, EPD0711_2_A04, EPD0711_2_B01, EPD0711_2_B03, EPD0711_2_B04, EPD0711_2_C01, EPD0711_2_C02, EPD0711_2_C03, EPD0711_2_C04, EPD0711_2_D01, EPD0711_2_D02, EPD0711_2_D03, EPD0711_2_D04, EPD0711_2_E02, EPD0711_2_E03, EPD0711_2_F01, EPD0711_2_F02, EPD0711_2_F03, EPD0711_2_F04, EPD0711_2_G02, EPD0711_2_G04, EPD0711_2_H02, EPD0711_2_H03 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 6146 starting at position 25097717 and ending at position 25103863 of Chromosome 13 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
(J:155845, J:173534)
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Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
All: |
2 reference(s) |
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