Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pitx2tm1.1Mbf
Name:	paired-like homeodomain transcription factor 2; targeted mutation 1.1, Milena B Furtado
MGI ID:	MGI:4880738
Synonyms:	Pitx2flox
Gene:	Pitx2  Location: Chr3:128993527-129013240 bp, + strand  Genetic Position: Chr3, 57.84 cM
Alliance:	Pitx2tm1.1Mbf page

Germline Transmission:	Earliest citation of germline transmission: J:167616
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 5, and a neo cassette with a 3' loxP site was inserted downstream of exon 5. (J:167616)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pitx2 Mutation:	38 strains or lines available

Original:	J:167616 Furtado MB, et al., Characterization of Pitx2c expression in the mouse heart using a reporter transgene. Dev Dyn. 2011 Jan;240(1):195-203
All:	2 reference(s)