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Tg(H2-K1-tsA58)6Kio
Transgene Detail
Summary
Symbol: Tg(H2-K1-tsA58)6Kio
Name: transgene insertion 6, Dimitris Kioussis
MGI ID: MGI:4868476
Synonyms: H-2K(b)-tsA58, immorto, Immortomouse, Tg(H2-K1-tsA58), Tg(H2Kb-tsA58)6Kio
Transgene: Tg(H2-K1-tsA58)6Kio  Location: unknown  
Alliance: Tg(H2-K1-tsA58)6Kio page
Transgene
origin
Strain of Origin:  (CBA/Ca x C57BL/10)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe 5' flanking promoter and transcriptional start site of the mouse H-2Kb gene was fused to the SV40 tsA58 early region coding sequence. Thirty-four mice carrying from one to five copies of the transgene were born. Several lines were analysed including line 6 and 11. (J:126941)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:126941 Jat PS, et al., Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5096-100
All:  60 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory