About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:74055 Merves M, et al., Developmental expression of aquaporin 2 in the mouse inner ear. Laryngoscope. 2000 Nov;110(11):1925-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4867235
Gene symbol: Aqp2
Gene name: aquaporin 2
Antibody: anti-AQP2 (GN-762)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: otocyst epithelium Present Diffuse 3 Expression is along the luminal surface.

Specimen Not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: vestibular component epithelium Very strong Regionally restricted Expression is in the medial region of the vestibule.
TS20: cochlear duct epithelium Strong Diffuse
TS20: vestibulo-cochlear ganglion Weak Non-Uniform

Specimen 4B,E: embryonic day 13.0 (more )
Note: (E) is a higher magnification of the vestibule area in (B).
Structure Level Pattern Image Note
TS21: inner ear vestibular component Strong Regionally restricted 4B , 4E Expression is in the medial aspect.
TS21: cochlear duct epithelium Strong 4B Expression is in the luminal epithelium.
TS21: endolymphatic duct Absent 4B
TS21: endolymphatic sac Absent 4B

Specimen 4C: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: endolymphatic sac Absent 4C

Specimen 4D: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: semicircular canal Present Regionally restricted 4D Expression is in the epithelium of the ampullae in the regions of the cristae.

Specimen 4F: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: cochlear duct epithelium Present 4F

Specimen 5A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: saccule Present Regionally restricted 5A Expression is in the maculae.
TS23: utricle Present Regionally restricted 5A Expression is in the maculae.

Specimen 5B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 5B Expression is in turns and is strong in the apical turn of the cochlea.
TS23: cochlear ganglion Present 5B

Specimen 5C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 5C Expression is in turns and is strong in the midturn of the cochlea.

Specimen 5E: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 5E Expression is in a patch located along the inferior lateral aspect of the duct and in a band in a more superior lateral position.

Specimen 6A: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: vestibulocochlear nerve cochlear component Present 6A
TS26: cochlear duct epithelium Trace 6A

Specimen 6B: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: endolymphatic sac mesenchyme Present Regionally restricted 6B Expression is in a rim adjacent to the basal laminae of the sac epithelium.
TS26: endolymphatic sac epithelium Present Non-Uniform 6B

Specimen 6C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cochlear duct epithelium Present Regionally restricted 6C Expression is in several patches along the developing Reissner's membrane, superior portion of the presumptive stria vascularis, and spiral limbus region.

Specimen 6D: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: utricle Present Regionally restricted 6D Expression is in the lateral walls of the utricle and in regions immediately adjacent to the cristae.
TS26: saccule Present 6D
TS26: semicircular duct ampulla Present 6D
TS26: crista ampullaris Present Regionally restricted 6D Expression is in nerve fibers innervating the crista.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/21/2024
MGI 6.23
The Jackson Laboratory