Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fth1tm1.1Lck
Name:	ferritin heavy polypeptide 1; targeted mutation 1.1, Lukas C Kuhn
MGI ID:	MGI:4847958
Synonyms:	Fthlox
Gene:	Fth1  Location: Chr19:9957962-9962462 bp, + strand  Genetic Position: Chr19, 6.23 cM, cytoband A-C
Alliance:	Fth1tm1.1Lck page

Germline Transmission:	Earliest citation of germline transmission: J:166515
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Flp-mediated recombination removed the neo cassette leaving the promoter and exon 1 floxed. (J:166515)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fth1 Mutation:	14 strains or lines available

Original:	J:166515 Darshan D, et al., Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage. Hepatology. 2009 Sep;50(3):852-60
All:	23 reference(s)