Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atp11cm1Btlr
Name:	ATPase, class VI, type 11C; mutation 1, Bruce Beutler
MGI ID:	MGI:4843273
Synonyms:	emptyhive
Gene:	Atp11c  Location: ChrX:59268643-59450041 bp, - strand  Genetic Position: ChrX, 33.5 cM, cytoband A5
Alliance:	Atp11cm1Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: The mutation corresponds to a C to T transition at nucleotide position 2113 of the transcript that replaces a triplet encoding glutamine to a termination codon at amino acid position 655 (Q655Ter). (J:171925) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atp11c Mutation:	16 strains or lines available

Original:	J:171925 Siggs OM, et al., The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow. Nat Immunol. 2011 May;12(5):434-40
All:	4 reference(s)