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Tg(Prnp-TARDBP)4Jlel
Transgene Detail
Summary
Symbol: Tg(Prnp-TARDBP)4Jlel
Name: transgene insertion 4, Jeffrey L Elliott
MGI ID: MGI:4839645
Synonyms: WT TDP-43 line 4
Transgene: Tg(Prnp-TARDBP)4Jlel  Location: unknown  
Alliance: Tg(Prnp-TARDBP)4Jlel page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Prnp-TARDBP)4Jlel expresses 1 gene
 
Mutation detailsThe mouse promoter drives neuronal expression of the wild-type human cDNA. Several lines were established (including 4, 13, and 21). (J:165985)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:165985 Stallings NR, et al., Progressive motor weakness in transgenic mice expressing human TDP-43. Neurobiol Dis. 2010 Nov;40(2):404-14
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory