Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Myh9tm5Rsad
Name:	myosin, heavy polypeptide 9, non-muscle; targeted mutation 5, Robert S Adelstein
MGI ID:	MGI:4838521
Synonyms:	Myh9flox, NMII-Aflox
Gene:	Myh9  Location: Chr15:77644787-77726375 bp, - strand  Genetic Position: Chr15, 36.81 cM
Alliance:	Myh9tm5Rsad page

Germline Transmission:	Earliest citation of germline transmission: J:164684
Parent Cell Line:	CMT-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 3 and a neo cassette with a 3' loxP site was inserted downstream of exon 3. (J:164684)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	66 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myh9 Mutation:	218 strains or lines available

Original:	J:164684 Jacobelli J, et al., Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions. Nat Immunol. 2010 Oct;11(10):953-61
All:	30 reference(s)