Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcnn2bc-6J
Name:	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; bouncy 6 Jackson
MGI ID:	MGI:4834267
Gene:	Kcnn2  Location: Chr18:45401927-45818950 bp, + strand  Genetic Position: Chr18, 24.34 cM, cytoband C
Alliance:	Kcnn2bc-6J page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: A failed complementation test with bouncy 3 Jackson proved the two allelic and exome sequencing identified a single G-to-A transversion at chromosome 18 position 45,685,419 (GRCm38) in bouncy 6 Jackson, which causes a nonsense mutation changing tryptophan to a stop codon at residue 345 in the last exon (NP_536713:p.W345*, ENSMUSP00000067884:p.W610*, NP_001299834:p.W620*). (J:215011, J:222308) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kcnn2 Mutation:	43 strains or lines available

Original:	J:215011 Harris BS, et al., The bouncy 6 Jackson allele of Kcnn2. MGI Direct Data Submission. 2014;
All:	2 reference(s)