Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(PER2*S662D)405Ljp
Name:	transgene insertion 405, Louis J Ptacek
MGI ID:	MGI:4833973
Synonyms:	hPer2 S662D
Transgene:	Tg(PER2*S662D)405Ljp  Location: unknown
Alliance:	Tg(PER2*S662D)405Ljp page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(PER2*S662D)405Ljp expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human PER2 (8864) Per2  (MGI:1195265)   Mutation details: The full-length sequence of the human PER2 gene carried in BAC RP11-139K17 was modified to change serine residue 662 to aspartic acid (S662D, AGT->GAT). Several lines were generated. (J:126404)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:126404 Xu Y, et al., Modeling of a human circadian mutation yields insights into clock regulation by PER2. Cell. 2007 Jan 12;128(1):59-70
All:	1 reference(s)