Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Glg1tm1Brle
Name:	golgi apparatus protein 1; targeted mutation 1, Brendan Lee
MGI ID:	MGI:4829764
Gene:	Glg1  Location: Chr8:111881053-111985848 bp, - strand  Genetic Position: Chr8, 57.98 cM
Alliance:	Glg1tm1Brle page

Germline Transmission:	Earliest citation of germline transmission: J:163721
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 13 through 16 were replaced with a puro cassette and 3' Hprt minigene. The absence of protein expression was confirmed by western blot on brain extracts. (J:163721)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Glg1 Mutation:	64 strains or lines available

Original:	J:163721 Yang T, et al., E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta. J Clin Invest. 2010 Jul 1;120(7):2474-85
All:	3 reference(s)