Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Psmg1tm1.2Smta
Name:	proteasome (prosome, macropain) assembly chaperone 1; targeted mutation 1.2, Shigeo Murata
MGI ID:	MGI:4820730
Gene:	Psmg1  Location: Chr16:95781133-95792160 bp, - strand  Genetic Position: Chr16, 56.76 cM
Alliance:	Psmg1tm1.2Smta page

Germline Transmission:	Earliest citation of germline transmission: J:162790
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre mediated recombination removed exon 2. The absence of protein expression was confirmed by immunohistochemistry on E6 embryos in utero. (J:162790)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Psmg1 Mutation:	20 strains or lines available

Original:	J:162790 Sasaki K, et al., PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis. Mol Cell Biol. 2010 Aug;30(15):3864-74
All:	1 reference(s)