About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:160843 Yang M, et al., Sm22alpha transcription occurs at the early onset of the cardiovascular system and the intron 1 is dispensable for its transcription in smooth muscle cells during mouse development. Int J Physiol Pathophysiol Pharmacol. 2010 Jan 1;2(1):12-19
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:4820424
Gene symbol: Tagln
Gene name: transgelin
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 7.5; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS11: chorion Present 2A Expression in the area of chorion formation.
TS11: embryo Present Regionally restricted 2A Expression in cells lying medial and immediately cranial to the cardiac crescent.

Specimen 2B: embryonic day 7.75; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS11: heart Strong Regionally restricted 2B High expression in the heart tube caudal to the head fold.

Specimen 2C: embryonic day 8.0; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS12: heart Present Regionally restricted 2C Authors state that expression expanded rapidly and progressively toward the arterial pole as the heart tube forms.

Specimen 2D: embryonic day 8.0; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS12: primitive heart tube Present Regionally restricted 2D Authors state that expression expanded rapidly and progressively toward the arterial pole as the heart tube forms.

Specimen 2E: embryonic day 8.5; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS13: heart Strong 2E
TS13: dorsal aorta Absent 2E
TS13: somite Absent 2E

Specimen 3A: embryonic day 9.0; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS14: heart Strong 3A
TS14: dorsal aorta Absent 3A
TS14: somite Absent 3A

Specimen 3B: embryonic day 10.0; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS16: heart Present 3B
TS16: dorsal aorta Strong 3B Increased expression in aorta and somites.
TS16: somite Strong 3B Increased expression in aorta and somites.

Specimen 3C: embryonic day 12.0; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS20: heart Weak 3C Diminishing expression in heart and somites.
TS20: somite Weak 3C Diminishing expression in heart and somites.
TS20: dorsal aorta Strong 3C Prominent expression in aorta.
TS20: arterial system Strong 3C Clear expression in branches of arteries throughout the embryo, including those extending into the brain.

Specimen 3D: embryonic day 13.0; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS21: heart Absent 3D
TS21: somite Absent 3D
TS21: arterial system Strong 3D
TS21: dorsal aorta Strong 3D
TS21: pulmonary artery Present 3D
TS21: esophagus Strong 3D High expression in visceral organs such the lung, esophagus, stomach, intestine, and bladder.
TS21: intestine Strong 3D High expression in visceral organs such the lung, esophagus, stomach, intestine, and bladder.
TS21: primitive bladder Strong 3D High expression in visceral organs such the lung, esophagus, stomach, intestine, and bladder.
TS21: stomach Strong 3D High expression in visceral organs such the lung, esophagus, stomach, intestine, and bladder.

Specimen 4A: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: aorta Present 4A
TS28: coronary artery Present 4A
TS28: cardiac muscle tissue Absent 4A

Specimen 4B: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: lung Present Regionally restricted 4B
TS28: pulmonary artery Strong 4B
TS28: pulmonary vein Strong 4B

Specimen 4C: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: intestine Strong 4C

Specimen 4D: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: upper leg Present Regionally restricted 4D
TS28: femoral artery Present 4D
TS28: femoral vein Present 4D

Specimen 4E: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: stomach Strong 4E
TS28: esophagus Absent 4E

Specimen 4F: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: bladder Strong 4F

Specimen 4G: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: upper leg Present Regionally restricted 4G
TS28: femoral artery Present 4G
TS28: femoral vein Present 4G
TS28: adipose tissue Absent 4G
TS28: nerve Absent 4G
TS28: skeletal muscle Absent 4G

Specimen 4H: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: lung Present Regionally restricted 4H
TS28: pulmonary vein Strong 4H
TS28: alveolus epithelium Absent 4H No expression in the simple squamous epithelium of alveoli.

Specimen 4I: postnatal adult; Taglntm1Liw/Tagln+ (more )
Structure Level Pattern Image Note
TS28: intestine Present Regionally restricted 4I
TS28: intestine smooth muscle Present 4I Expression in the muscularis externa consisting of both circular and longitudinal smooth muscle layers.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory