Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(S100a4-EGFP)M1Egn
Name:	transgene insertion M1, Eric G Neilson
MGI ID:	MGI:4819359
Synonyms:	FSP1.gfp, Tg(Fsp1-GFP)
Transgene:	Tg(S100a4-EGFP)M1Egn  Location: unknown
Alliance:	Tg(S100a4-EGFP)M1Egn page

Strain of Origin:

C57BL/6 x DBA/2

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: The transgenic construct containing sequence encoding EGFP under the control of the mouse S100a4, S100 calcium binding protein A4, promoter. These transgenic mice express GFP under the control of the mouse S100a4, S100 calcium binding protein A4, promoter. All tissue fibroblasts in adult hemizygous mice fluoresce. Woods light examination of the eyes of adult transgenic mice reveal green fluorescence of the fibroblasts of the cornea. Green fluorescing fibroblasts are detected in kidney, liver, lung and heart and occasionally in interstitial organ spaces. Founder line M1 was established. (J:111660)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:111660 Iwano M, et al., Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest. 2002 Aug;110(3):341-50
All:	17 reference(s)