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Dclk1tm1.2Jgg
Targeted Allele Detail
Summary
Symbol: Dclk1tm1.2Jgg
Name: doublecortin-like kinase 1; targeted mutation 1.2, Joseph G Gleeson
MGI ID: MGI:4819273
Gene: Dclk1  Location: Chr3:55149785-55446489 bp, + strand  Genetic Position: Chr3, 26.53 cM, cytoband D
Alliance: Dclk1tm1.2Jgg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105300
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 3 was flanked by loxP sites and a 3' floxed PGK-neo resistance cassette. Cre mediated recombination removed the neo cassette leaving exon 3 floxed. (J:105300)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dclk1 Mutation:  53 strains or lines available
References
Original:  J:105300 Koizumi H, et al., Doublecortin-like kinase functions with doublecortin to mediate fiber tract decussation and neuronal migration. Neuron. 2006 Jan 5;49(1):55-66
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory