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Gene Expression Data
Assay Details
Assay
Reference: J:161870 Wagenaar GT, et al., Expression patterns of protein C inhibitor in mouse development. J Mol Histol. 2010 Feb;41(1):27-37
Assay type: RNA in situ
MGI Accession ID: MGI:4818462
Gene symbol: Serpina5
Gene name: serine (or cysteine) peptidase inhibitor, clade A, member 5
Probe: PCI cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen Not shown E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Absent

Specimen Not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Absent

Specimen Not shown E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Absent

Specimen 1a,c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lobar bronchus Present Regionally restricted 1c , 1a

Specimen 2b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 2b Expression is in the choroid plexus.

Specimen 2c: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: oral epithelium Present 2c

Specimen 2e: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: esophagus epithelium Present 2e
TS19: lung epithelium Present 2e
TS19: trachea Absent 2e

Specimen 2g: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung epithelium Present Regionally restricted 2g Expression is in distal tubules, absent in proximal tubules.

Specimen 2i: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: stomach Present Regionally restricted 2i Expression is in the cardiac region of the stomach where the oesophagus enters.

Specimen 3a: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: choroid plexus Present 3a

Specimen 3c,d: embryonic day 16.5 (more )
Note: d high power magnification of boxed area in (c)
Structure Level Pattern Image Note
TS24: diaphragm Present 3c , 3d
TS24: intercostal muscle Present 3c , 3d
TS24: pectoral girdle and thoracic body wall musculature Present 3c , 3d
TS24: bronchiole epithelium Present Regionally restricted 3c , 3d Expression is in distal branching bronchioli and no staining in proximal tubules.

Specimen 4b: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: esophagus Strong 4b
TS22: hindlimb skin Strong 4b
TS22: gut epithelium Present Scattered 4b Sporadic expression.
TS22: stomach epithelium Present Regionally restricted 4b Expression is in the proximal part.

Specimen 4c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: esophagus Strong 4c

Specimen 4d: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: urethra Strong 4d
TS22: anal canal caudal part epithelium Strong 4d

Specimen 4e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal tubule Present Scattered 4e

Specimen 4f: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nephric duct of male, mesonephric portion Present 4f Expression is in the epididymis.
TS22: testis Present 4f

Specimen 5a,b: embryonic day 18.5 (more )
Note: b high power magnification of boxed area in (a)
Structure Level Pattern Image Note
TS26: bronchiole epithelium Strong Regionally restricted 5a , 5b Expression is in columnar epithelia of terminal bronchioli.
TS26: lung epithelium Weak Regionally restricted 5a , 5b Expression is in type 2 alveolar epithelial cells, type 1 epithelial cells of sacculi are devoid of signal.

Specimen 5e,f: postnatal day 2 (more )
Note: f high power magnification of boxed area in (e)
Structure Level Pattern Image Note
TS27: bronchiole epithelium Present Regionally restricted 5e , 5f Expression is in terminal bronchii in Clara cells until the bronchoalveolar duct junction.
TS27: alveolus epithelium Weak Regionally restricted 5e , 5f Expression is in type 2 alveolar cells, type 1 alveolar cells are negative.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory