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Gene Expression Data
Assay Details
Assay
Reference: J:161870 Wagenaar GT, et al., Expression patterns of protein C inhibitor in mouse development. J Mol Histol. 2010 Feb;41(1):27-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4818396
Gene symbol: Serpina5
Gene name: serine (or cysteine) peptidase inhibitor, clade A, member 5
Antibody: mPCI antibody
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1e,g: embryonic day 16.5 (more )
Note: (g) high power magnification of boxed areas in (e).
Structure Level Pattern Image Note
TS24: lobar bronchus Present Regionally restricted 1e , 1g Expression is in the distal branching tubules of the lung and is absent in proximal tubules.

Specimen 2a: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 2a

Specimen 2d: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present 2d
TS19: atrioventricular canal Absent 2d
TS19: outflow tract Absent 2d Absent in non-myocradial cells such as the developing valves in the outflow tract.

Specimen 2f: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung epithelium Present Regionally restricted 2f Expression is in distal tubules, absent in proximal tubules.

Specimen 2h: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: stomach Present Regionally restricted 2h Expression is in the cardiac region of the stomach where the oesophagus enters.

Specimen 2j: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: urinary system Present Regionally restricted 2j Expression is in the urethra.
TS19: gonad Present 2j
TS19: hindgut Present 2j
TS19: hindgut diverticulum postanal component epithelium Present 2j

Specimen 3b: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal cavity Present 3b
TS22: oral epithelium Present 3b
TS22: vibrissa Present 3b
TS22: head Present Regionally restricted 3b Expression is in the snout.

Specimen 3e,f: embryonic day 16.5 (more )
Note: (f) high power magnification of boxed area in (e).
Structure Level Pattern Image Note
TS24: bronchiole epithelium Present Regionally restricted 3f , 3e Expression is in distal branching bronchioli and no staining in proximal tubules.
TS24: rib Present 3f , 3e

Specimen 3g: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: esophagus epithelium Present 3g
TS24: trachea Absent 3g

Specimen 3h: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: intercostal muscle Present 3h
TS22: skin Present 3h

Specimen 4a: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: liver Absent 4a
TS22: pancreas Absent 4a

Specimen 4g: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: autopod skin Present 4g
TS24: limb interdigital region Present 4g
TS24: limb skeleton Present Regionally restricted 4g Expression is in the zone of beginning ossification in diaphyses.

Specimen 4h: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vertebra Present Regionally restricted 4h Expression is around areas of developing intervertebral discs.

Specimen 5c,d: postnatal day 1 (more )
Note: (d) high power magnification of boxed area in (c).
Structure Level Pattern Image Note
TS27: bronchiole epithelium Present Regionally restricted 5d , 5c Expression is in terminal bronchii in Clara cells until the bronchoalveolar duct junction.
TS27: alveolus epithelium Weak Regionally restricted 5d , 5c Expression is in type 2 alveolar cells, type 1 alveolar cells are negative.

Specimen 5g,h: postnatal adult (more )
Note: (h) high power magnification of boxed area in (g).
Structure Level Pattern Image Note
TS28: lung Absent 5h , 5g


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory