Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ago2tm2Ghan
Name:	argonaute RISC catalytic subunit 2; targeted mutation 2, Greggory J Hannon
MGI ID:	MGI:4462370
Synonyms:	Ago2mc
Gene:	Ago2  Location: Chr15:72967693-73056777 bp, - strand  Genetic Position: Chr15, 33.92 cM
Alliance:	Ago2tm2Ghan page

Germline Transmission:	Earliest citation of germline transmission: J:161968
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A 5'HPRT mini gene and puro cassette were inserted into the PAZ domain. (J:161968)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ago2 Mutation:	54 strains or lines available

Original:	J:161968 Cheloufi S, et al., A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature. 2010 Jun 3;465(7298):584-9
All:	1 reference(s)