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C1galt1c1tm1.1Rdcu
Targeted Allele Detail
Summary
Symbol: C1galt1c1tm1.1Rdcu
Name: C1GALT1-specific chaperone 1; targeted mutation 1.1, Richard D Cummings
MGI ID: MGI:4459539
Synonyms: Cosmcflox
Gene: C1galt1c1  Location: ChrX:37719662-37723964 bp, - strand  Genetic Position: ChrX, 22.91 cM, cytoband A2
Alliance: C1galt1c1tm1.1Rdcu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160290
Parent Cell Line:  HZ2.2 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe coding region exon was replaced with a floxed exon for the open reading frame and floxed neo cassette. Cre mediated recombination removed the neo cassette leaving the coding exon floxed. (J:160290)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any C1galt1c1 Mutation:  16 strains or lines available
References
Original:  J:160290 Wang Y, et al., Cosmc is an essential chaperone for correct protein O-glycosylation. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9228-33
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory