Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hes5tm1Kag
Name:	hes family bHLH transcription factor 5; targeted mutation 1, Ryoichiro Kageyama
MGI ID:	MGI:4459527
Synonyms:	Hes5-nlsLacZ
Gene:	Hes5  Location: Chr4:155045380-155046828 bp, + strand  Genetic Position: Chr4, 86.01 cM
Alliance:	Hes5tm1Kag page

Germline Transmission:	Earliest citation of germline transmission: J:159019
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region of the Hes5 gene was replaced by the IRES-nls-LacZ expression cassette.by homologous recombination. (J:159019)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Hes5 Mutation:	16 strains or lines available

Original:	J:159019 Imayoshi I, et al., Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. J Neurosci. 2010 Mar 3;30(9):3489-98
All:	6 reference(s)