Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Faap20tm1(KOMP)Mbp
Name:	Fanconi anemia core complex associated protein 20; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID:	MGI:4456552
Gene:	Faap20  Location: Chr4:155334259-155341144 bp, + strand  Genetic Position: Chr4, 86.17 cM
Alliance:	Faap20tm1(KOMP)Mbp page
IMPC:	Faap20 gene page

Mutant Cell Lines:	DEPD00507_1_A09, DEPD00507_1_A10, DEPD00507_1_A11, DEPD00507_1_A12, DEPD00507_1_B09, DEPD00507_1_B11, DEPD00507_1_B12, DEPD00507_1_C09, DEPD00507_1_C10, DEPD00507_1_C11, DEPD00507_1_D09, DEPD00507_1_D11, DEPD00507_1_D12, DEPD00507_1_E11, DEPD00507_1_E12, DEPD00507_1_F09, DEPD00507_1_F10, DEPD00507_1_F11, DEPD00507_1_F12, DEPD00507_1_G09, DEPD00507_1_G10, DEPD00507_1_G12, DEPD00507_1_H09
Germline Transmission:	Earliest citation of germline transmission: J:204812
Parent Cell Line:	JM8A3 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 740 starting at position 155334923 and ending at position 155335663 of Chromosome 4 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064, J:224688)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	27 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Faap20 Mutation:	16 strains or lines available

Original:	J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:	3 reference(s)