About   Help   FAQ
Arf6tm1(KOMP)Mbp
Targeted Allele Detail
Summary
Symbol: Arf6tm1(KOMP)Mbp
Name: ADP-ribosylation factor 6; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID: MGI:4454036
Gene: Arf6  Location: Chr12:69418924-69420557 bp, + strand  Genetic Position: Chr12, 28.81 cM
IMPC: Arf6 gene page
Mutation
origin
Mutant Cell Lines:  DEPD00516_5_A05, DEPD00516_5_B06, DEPD00516_5_D05, DEPD00516_5_D06, DEPD00516_5_D07, DEPD00516_5_D08, DEPD00516_5_E05, DEPD00516_5_F07, DEPD00516_5_F08, DEPD00516_5_G05
Germline Transmission:  Unknown
Parent Cell Line:  JM8A1.N3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsThe insertion of the L1L2_Bact_P cassette created a deletion of size 1459 starting at position 69419096 and ending at position 69420555 of Chromosome 12 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Arf6 Mutation:  10 strains or lines available
References
Original:  J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory