Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ccdc121tm1(KOMP)Mbp
Name:	coiled-coil domain containing 121; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID:	MGI:4454022
Gene:	Ccdc121  Location: Chr5:31643205-31645820 bp, + strand  Genetic Position: Chr5, 17.27 cM, cytoband B1
IMPC:	Ccdc121 gene page

Mutant Cell Lines:	DEPD00517_3_A09, DEPD00517_3_A10, DEPD00517_3_A11, DEPD00517_3_A12, DEPD00517_3_B09, DEPD00517_3_B10, DEPD00517_3_B11, DEPD00517_3_B12, DEPD00517_3_C10, DEPD00517_3_C12, DEPD00517_3_D09, DEPD00517_3_D10, DEPD00517_3_D12, DEPD00517_3_E10, DEPD00517_3_E11, DEPD00517_3_E12, DEPD00517_3_F09, DEPD00517_3_F10, DEPD00517_3_F12, DEPD00517_3_G11, DEPD00517_3_G12, DEPD00517_3_H11, DEPD00517_3_H12
Germline Transmission:	Unknown
Parent Cell Line:	JM8A1.N3 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1226 starting at position 31644596 and ending at position 31645822 of Chromosome 5 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Ccdc121 Mutation:	23 strains or lines available

Original:	J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:	1 reference(s)