Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Cfap141tm1(KOMP)Wtsi
Name:	cilia and flagella associated protein 141; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID:	MGI:4451288
Gene:	Cfap141  Location: Chr3:89970103-89973182 bp, + strand  Genetic Position: Chr3, 39.2 cM, cytoband F2
IMPC:	Cfap141 gene page

Mutant Cell Lines:	EPD0465_5_A02, EPD0465_5_B01, EPD0465_5_C02, EPD0465_5_C04, EPD0465_5_D03, EPD0465_5_F03, EPD0465_5_G01, EPD0465_5_G02
Germline Transmission:	Unknown
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1607 starting at position 89970398 and ending at position 89972005 of Chromosome 3 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Cfap141 Mutation:	4 strains or lines available

Original:	J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:	2 reference(s)