Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fzd8tm1Nat
Name:	frizzled class receptor 8; targeted mutation 1, Jeremy Nathans
MGI ID:	MGI:4442631
Synonyms:	Fz8lacZ
Gene:	Fzd8  Location: Chr18:9212856-9216201 bp, + strand  Genetic Position: Chr18, 4.91 cM
Alliance:	Fzd8tm1Nat page

Germline Transmission:	Earliest citation of germline transmission: J:159436
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The open reading frame of the targeted gene was replaced by beta-galactosidase (LacZ) via homologous recombination in a 129-derived embryonic stem (ES) cell line. A PGK-neo selectable marker used for ES cell selection is present downstream of the LacZ sequences. (J:159436, J:170839)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fzd8 Mutation:	33 strains or lines available

Original:	J:159436 Nathans J, DDS for Fzd8tm1Nat. MGI Direct Data Submission. 2010;
All:	4 reference(s)