Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Gad1tm1.1Bgc Name: glutamate decarboxylase 1; targeted mutation 1.1, Brian G Condie MGI ID: MGI:4442416 Synonyms: Gad1lacZ Gene: Gad1  Location: Chr2:70391644-70432358 bp, + strand  Genetic Position: Chr2, 41.63 cM, cytoband D Alliance: Gad1tm1.1Bgc page

Umbilical hernia in Gad1tm1.1Bgc/Gad1tm1.1Bgc mice Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:158888
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A cassette containing LacZ and a floxed MC1Neo was inserted into exon 2 producing an in frame fusion via homologous recombination. The neo was removed by Cre mediated recombination. (J:159165)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gad1 Mutation:	64 strains or lines available

Original:	J:159165 Westmoreland JJ, et al., Neuronal development of embryonic stem cells: a model of GABAergic neuron differentiation. Biochem Biophys Res Commun. 2001 Jun 15;284(3):674-80
All:	2 reference(s)