Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Prkralear Name: protein kinase, interferon inducible double stranded RNA dependent activator; little ears MGI ID: MGI:4442387 Gene: Prkra  Location: Chr2:76460242-76478359 bp, - strand  Genetic Position: Chr2, 45.07 cM Alliance: Prkralear page

Small ears and smaller body size of Prkralear/Prkralear female (left) compared to heterozygote (right) at nine weeks of age Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

C57BL/6J

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: This spontaneous mutation has a T-to-A transversion at chromosome 2:76,639,197 (GRCm38) in intron 5 immediately adjacent to the conserved splice donor site. (J:176116, J:222308, J:223062) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prkra Mutation:	23 strains or lines available

Original:	J:159349 Curtain MM, et al., An Ear Pinna Mutation in the Mouse on Chromosome Two. MGI Direct Data Submission. 2010;
All:	5 reference(s)