Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ahi1tm2.1Jgg
Name:	Abelson helper integration site 1; targeted mutation 2.1, Joseph G Gleeson
MGI ID:	MGI:4437788
Gene:	Ahi1  Location: Chr10:20828446-20956328 bp, + strand  Genetic Position: Chr10, 9.75 cM, cytoband A3
Alliance:	Ahi1tm2.1Jgg page

Germline Transmission:	Earliest citation of germline transmission: J:158019
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 6 and a floxed neo cassette was inserted downstream of exon 7. Cre-mediated recombination removed the neo cassette leaving exon 6 through 7 floxed. (J:158019)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ahi1 Mutation:	80 strains or lines available

Original:	J:158019 Louie CM, et al., AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis. Nat Genet. 2010 Feb;42(2):175-80
All:	1 reference(s)