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Gene Expression Data
Assay Details
Assay
Reference: J:157352 Loftus SK, et al., Comparison of melanoblast expression patterns identifies distinct classes of genes. Pigment Cell Melanoma Res. 2009 Oct;22(5):611-22
Assay type: RNA in situ
MGI Accession ID: MGI:4437033
Gene symbol: Gpnmb
Gene name: glycoprotein (transmembrane) nmb
Probe: Gpnmb cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3 C57BL/6J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate Expression is in melanoblasts.
TS19: eye Present

Specimen 3 Mitf Mi/+: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate The density of expressing melanoblasts is reduced.
TS19: eye Present

Specimen 3 Mitf Mi/Mi: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Absent
TS19: eye Absent

Specimen 3 Sox10 LacZ/+: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate The density of expressing melanoblasts is reduced.
TS19: eye Present

Specimen 3 Sox10 LacZ/LacZ: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate The density of expressing melanoblasts is severely reduced.
TS19: eye Present

Specimen 5A Mitf+/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Present 5_Mitf +/+ Gpnmb

Specimen 5A Mitf Mi/+: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Weak 5_Mitf Mi/+ Gpnmb

Specimen 5A Mitf Mi/Mi: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Absent 5_Mitf Mi/Mi Gpnmb

Specimen sl_Gpmnb_+_+_b_tail_40: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Gpmnb_+_+_b_tail_40 Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_a_fore_25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_a_fore_25 Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_a_head_25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_a_head_25 Expression is in melanoblasts.
TS19: eye Present sl_Gpnmb_+_+_a_head_25

Specimen sl_Gpnmb_+_+_a_head_40: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_a_head_40 Expression is in melanoblasts.
TS19: eye Present sl_Gpnmb_+_+_a_head_40

Specimen sl_Gpnmb_+_+_a_hind_25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_a_hind_25 Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_a_hind_40: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_a_hind_40 Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_a_side_16-20: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_a_side_16-20 Expression is in melanoblasts.
TS19: eye Present sl_Gpnmb_+_+_a_side_16-20

Specimen sl_Gpnmb_+_+_a_tail_40: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_a_tail_40 Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_a_tail_40a: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_a_tail_40a Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_b_fore_25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_b_fore_25 Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_b_head_25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_b_head_25 Expression is in melanoblasts.
TS19: eye Present sl_Gpnmb_+_+_b_head_25

Specimen sl_Gpnmb_+_+_b_head_40: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_b_head_40 Expression is in melanoblasts.
TS19: eye Present sl_Gpnmb_+_+_b_head_40

Specimen sl_Gpnmb_+_+_b_hind_25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_b_hind_25 Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_b_hind_40: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_b_hind_40 Expression is in melanoblasts.

Specimen sl_Gpnmb_+_+_b_side_16-20: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_+_+_b_side_16-20 Expression is in melanoblasts.
TS19: eye Present sl_Gpnmb_+_+_b_side_16-20

Specimen sl_Gpnmb_mi_+_a_fore_25: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_a_fore_25 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_mi_+_a_head_25: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_a_head_25 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_mi_+_a_head_25

Specimen sl_Gpnmb_mi_+_a_head_40: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_a_head_40 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_mi_+_a_head_40

Specimen sl_Gpnmb_mi_+_a_hind_25: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_a_hind_25 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_mi_+_a_hind_40: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_a_hind_40 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_mi_+_a_side_16-: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_a_side_16- The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_mi_+_a_side_16-

Specimen sl_Gpnmb_mi_+_a_side16-20: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_a_side16-20 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_mi_+_a_side16-20

Specimen sl_Gpnmb_mi_+_a_tail_40: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_a_tail_40 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_mi_+_b_head_40: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_mi_+_b_head_40 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_mi_mi_a_fore_25: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Gpnmb_mi_mi_a_fore_25

Specimen sl_Gpnmb_mi_mi_a_head_25: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Gpnmb_mi_mi_a_head_25 Absent in melanoblasts.
TS19: eye Absent sl_Gpnmb_mi_mi_a_head_25

Specimen sl_Gpnmb_mi_mi_a_head_40: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Gpnmb_mi_mi_a_head_40 Absent in melanoblasts.
TS19: eye Absent sl_Gpnmb_mi_mi_a_head_40

Specimen sl_Gpnmb_mi_mi_a_hind_25: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Gpnmb_mi_mi_a_hind_25

Specimen sl_Gpnmb_mi_mi_a_hind_40: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Gpnmb_mi_mi_a_hind_40

Specimen sl_Gpnmb_mi_mi_a_side_16-: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Absent sl_Gpnmb_mi_mi_a_side_16- Absent in melanoblasts.
TS19: eye Absent sl_Gpnmb_mi_mi_a_side_16-

Specimen sl_Gpnmb_mi_mi_a_side_16-20: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Absent sl_Gpnmb_mi_mi_a_side_16-20 Absent in melanoblasts.
TS19: eye Absent sl_Gpnmb_mi_mi_a_side_16-20

Specimen sl_Gpnmb_mi_mi_a_tail_40: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Absent sl_Gpnmb_mi_mi_a_tail_40

Specimen sl_Gpnmb_s10_+_a_fore_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_a_fore_25 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_s10_+_a_head_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_a_head_25 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_s10_+_a_head_25

Specimen sl_Gpnmb_s10_+_a_head_40: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_a_head_40 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_s10_+_a_head_40

Specimen sl_Gpnmb_s10_+_a_hind_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_a_hind_25 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_s10_+_a_hind_40: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present sl_Gpnmb_s10_+_a_hind_40 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_S10_+_a_side: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_S10_+_a_side The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_S10_+_a_side

Specimen sl_Gpnmb_s10_+_b_fore_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_b_fore_25 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_s10_+_b_head_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_b_head_25 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_s10_+_b_head_25

Specimen sl_Gpnmb_s10_+_b_head_40: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_b_head_40 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_s10_+_b_head_40

Specimen sl_Gpnmb_s10_+_b_hind_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_b_hind_25 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_s10_+_b_hind_40: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_b_hind_40 The density of expressing melanoblasts is reduced.

Specimen sl_Gpnmb_s10_+_b_side_16-20: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_b_side_16-20 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_s10_+_b_side_16-20

Specimen sl_Gpnmb_s10_+_b_side_16a: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_+_b_side_16a The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Gpnmb_s10_+_b_side_16a

Specimen sl_Gpnmb_s10_s10_a_fore_25: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Gpnmb_s10_s10_a_fore_25 Absent in melanoblasts.

Specimen sl_Gpnmb_s10_s10_a_head_25: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Gpnmb_s10_s10_a_head_25 Absent in melanoblasts.
TS19: eye Present sl_Gpnmb_s10_s10_a_head_25

Specimen sl_Gpnmb_s10_s10_a_head_40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Gpnmb_s10_s10_a_head_40 Absent in melanoblasts.
TS19: eye Present sl_Gpnmb_s10_s10_a_head_40

Specimen sl_Gpnmb_s10_s10_a_head_40a: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Gpnmb_s10_s10_a_head_40a Absent in melanoblasts.
TS19: eye Present sl_Gpnmb_s10_s10_a_head_40a

Specimen sl_Gpnmb_s10_s10_a_hind_25: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Gpnmb_s10_s10_a_hind_25 Absent in melanoblasts.

Specimen sl_Gpnmb_s10_s10_a_hind_40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Gpnmb_s10_s10_a_hind_40 Absent in melanoblasts.

Specimen sl_Gpnmb_s10_s10_a_hind_40b: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Gpnmb_s10_s10_a_hind_40b Absent in melanoblasts.

Specimen sl_Gpnmb_s10_s10_a_side: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_s10_a_side The density of expressing melanoblasts is reduced and is in the tail only.
TS19: eye Present sl_Gpnmb_s10_s10_a_side

Specimen sl_Gpnmb_s10_s10_a_side_16: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_s10_a_side_16 The density of expressing melanoblasts is reduced and is in the tail only.
TS19: eye Present sl_Gpnmb_s10_s10_a_side_16

Specimen sl_Gpnmb_S10_S10_a_tail40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Gpnmb_S10_S10_a_tail40 The density of expressing melanoblasts is reduced and is in the tail only.

Specimen sl_Gpnmb_s10_s10_b_head_25: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Gpnmb_s10_s10_b_head_25 Absent in melanoblasts.
TS19: eye Present sl_Gpnmb_s10_s10_b_head_25

Specimen sl_Gpnmb_s10_s10_b_side_16: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Gpnmb_s10_s10_b_side_16 The density of expressing melanoblasts is reduced and is in the tail only.

Specimen sl_Gpnmb_S10_S10_b_tail_40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Gpnmb_S10_S10_b_tail_40 The density of expressing melanoblasts is reduced and is in the tail only.


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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory