Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il4/Il13tm1.1Lky
Name:	interleukin 13; targeted mutation 1.1, Richard M Locksley
MGI ID:	MGI:4431368
Synonyms:	4-13F
Gene:	Il13  Location: Chr11:53522151-53525529 bp, - strand  Genetic Position: Chr11, 31.98 cM
Alliance:	Il4/Il13tm1.1Lky page

Germline Transmission:	Earliest citation of germline transmission: J:157129
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A single targeting event was used to insert a floxed Bsd resistance cassette between exon 2 and 3 of Il13 and an frt flanked neo cassette with a 3' loxP site downstream of exon 4 of Il4 . Flp and cre mediated recombination removed the selection cassettes leaving the region between exon 3 of Il13 and exon 4 of Il4 floxed. (J:157129)

Generation of the Il4/Il13tm1.1Lky allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Il13 Mutation:	29 strains or lines available

Original:	J:157129 Voehringer D, et al., Efficient generation of long-distance conditional alleles using recombineering and a dual selection strategy in replicate plates. BMC Biotechnol. 2009;9:69
All:	16 reference(s)