Hexb RT-PCR Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:149170 Martino S, et al., Neural precursor cell cultures from GM2 gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology. J Neurochem. 2009 Apr;109(1):135-47
Assay type:	RT-PCR
MGI Accession ID:	MGI:4430596
Gene symbol:	Hexb
Gene name:	hexosaminidase B

Probe:

Hexb-pC, Hexb-pD

Results

Image: 2b

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified (b)	Amount	Genetic Background	Mutant Allele(s)	Sex
E13	E13.0 (a)	TS21: brain	Present	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified
E18	E18.0 (a)	TS26: brain	Strong (c)	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified
P0	P0	TS27: brain	Strong	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified
P3	P3	TS27: brain	Strong (d)	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified
P6	P6	TS28: brain	Strong	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified
P13	P13	TS28: brain	Very strong (e)	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified
P21	P21	TS28: brain	Very strong (f)	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified
1M	P m 1	TS28: brain	Very strong (f)	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified
5M	P m 5	TS28: brain	Very strong (g)	0.125 µg; poly-A+ RNA	involves: 129S4/SvJae * C57BL/6	Hexb^tm1Rlp/Hexb^tm1Rlp	Not Specified

Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Expression was upregulated with age.
(c) 3.5- fold increase between E13 and E18
(d) 1.5-fold increase between P0 and P3
(e) 1.5-fold increase between P6 and P13
(f) Expression levels were then relatively stable up to adult age.
(g) 10-fold increase from E13 to adult.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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