Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Myh6-Ppara)404-4Dpk
Name:	transgene insertion 404-4, Daniel P Kelly
MGI ID:	MGI:4429461
Synonyms:	MHC-PPARalpha
Transgene:	Tg(Myh6-Ppara)404-4Dpk  Location: unknown
Alliance:	Tg(Myh6-Ppara)404-4Dpk page

Strain of Origin:

(C57BL/6 x CBA/J)F1

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Myh6-Ppara)404-4Dpk expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Ppara (MGI:104740)   Mutation details: This transgene consists of a 1.5-kb, NH2-terminal FLAG epitope-tagged Ppara cDNA downstream of the cardiac alpha myosin heavy chain promoter. This line exhibits Ppara protein levels about 15-fold more abundant in cardiac ventricles than in nontransgenics.(J:110580) (J:110580)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:110580 Finck BN, et al., The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest. 2002 Jan;109(1):121-30
All:	3 reference(s)